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Screening Information Data Set (SIDs) for High Production Volume Chemicals

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10 documents displayed.

Hexadecanoic (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/4016244.pdf
    Summary: Males were dosed for 47 days from day 14 before mating and females were dosed for 42-45 days from day 14 before mating to day 4 of lactation throughout the mating and pregnancy period. OECD SIDS HEXADECANOIC ACID UNEP PUBLICATIONS 14 Conclusion In an OECD combined repeated dose toxicity study with the reproduction/developmental toxicity screening test, there were no evidences of compound-related effects on reproduction/developmental parameters.

Glyoxal (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/107222.pdf
    Summary: OECD SIDS GLYOXAL UNEP Publications 144 In conclusion, the positive results in the Magnusson and Kligman test (2 studies), the Bühler test on guinea pigs and the LLNA test confirmed that Glyoxal can be considered as a sensitising substance. OECD SIDS GLYOXAL UNEP Publications 151 Table 4.3 In vitro genotoxicity tests with glyoxal on bacteria Test system Tested concentration range 1) (?g/plate) Metabolic activation system Result 2) Reference With Metab.activ.

Glycidyl methacrylate (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/106912.pdf
    Summary: OECD SIDS GLUCIDYL METHACRYLATE UNEP PUBLICATIONS FOREWORD INTRODUCTION GLUCIDYL METHACRYLATE CAS N°: 106-91-2 OECD SIDS GLYCIDYL METHACRYLATE UNEP Publications 2 COVER PAGE SIDS Initial Assessment Report for 10th SIAM (Japan, March 15-17, 2000) Chemical Name: Glycidyl methacrylate CAS No: 106-91-2 Sponsor Country: Japan and United States National SIDS Contact Point in Sponsor Country: Mr. Kazuhide Ishikawa Ministry of Foreign Affairs, Japan Mr. Oscar Hernandez US EPA HISTORY: SIDS Testing ...

Glycerol (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/56815.pdf
    Summary: OECD SIDS GLYCEROL UNEP PUBLICATIONS 11 The use of glycerol in tobacco products may lead to inhalation exposure as a constituent of tobacco smoke. OECD SIDS GLYCEROL UNEP PUBLICATIONS 17 Table 3.1.5 Repeated dose oral studies (excluding key study) Study type Species No. In vivo, glycerol produced no statistically significant effect OECD SIDS GLYCEROL UNEP PUBLICATIONS 22 in a chromosome aberrations and dominant lethal study.

Glutaraldehyde (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/111308.pdf
    Summary: OECD SIDS GLUTARALDEHYDE UNEP P bli i 12 The occupational exposure standard for glutaraldehyde in most OECD member countries is 0.2 ppm (peak limitation) with a 'sensitiser' notation. Manufacture of Glutaraldehyde Exposure data is available for plant workers involved in the manufacture and drumming of glutaraldehyde. Workplace atmospheric monitoring in Australian hospital x-ray facilities found that glutaraldehyde concentrations were generally less than 0.2 ppm, although concentrations up to ...

Fluorescent (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/FLUORESCENT.pdf
    Summary: There was no induction of cytogenetic effects in an in vitro chromosome aberration test in V79 cells, in an in vivo chromosome aberration test in spermatogonia (hamster), in a micronucleus test (mouse) and in a dominant lethal test (mouse, OECD TG 478, GLP). A 2-generation study in rats showed no evidence of reproduction toxicity (EPA OPPTS 870.3800, GLP): NOAEL = 300 mg/kg bw/day (parental toxicity); NOAEL = 1000 mg/kg bw/day (reproductive performance and offspring toxicity). Two studies ...

Formaldehyde (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/FORMALDEHYDE.pdf
    Summary: No reports on deaths following acute inhalation exposure were located (WHO IPCS, 1989) OECD SIDS FORMALDEHYDE UNEP PUBLICATIONS 14 Conclusion Evaluation: The major acute effects are a result of the irritating properties of formaldehyde. OECD SIDS FORMALDEHYDE UNEP PUBLICATIONS 17 3.1.5 Repeated Dose Toxicity Studies in Animals Inhalation The most extensive database is available for inhalation exposure in rats.

(FSD-Na) (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/FSD.pdf
    Summary: 98-612- PL, 9.Nov.1998, Bayer Corp., USA Bathe R., 6-Month oral (feeding) toxicity study in Beagle dogs, Research and Consulting Company, Report No.R 2730, Jan/10/1984 (at the request of Bayer AG) Bayer AG 1978; Internal Study, Acute toxicity to Leuciscus idus (August 1978) Bayer AG 1979, Internal Study, Bioaccumulation Study to Carp (05.04.1979) Bayer AG 1985a, Internal Study, Closed Bottle Test according to OECD Guideline 301 D (24.10.1985) Bayer AG 1985b, Internal Study, Acute toxicity to ...

5-Ethyl-2-picoline (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/104905.pdf
    Summary: Reference: [12] Test substance: 5-Ethyl-2-picoline, purity not specified Test species/strain: Rat Test method: No details given GLP: Not stated Test results: LC100 3.7 hrs = 1700 ppm Reference: [13] 6.1.3 Acute Dermal Toxicity Test substance: 5-Ethyl-2-picoline, purity not specified Test species/strain: Rabbit Test method: No details given GLP: Not stated Test results: LD50 = 1000 mg/kg Reference: [14] Test substance: 5-Ethyl-2-picoline, purity not specified Test species/strain: Guinea pig ...

Ethylenediamine (Screening Information Data Set - SIDs)
    12-13-05, http://www.inchem.org/documents/sids/sids/Ethylenediamine.pdf
    Summary: Industry prepared and resubmitted documents for consideration at SIAM 13. Testing: No testing ( x ) Testing ( ) Comments: Deadline for Circulation: September 14, 2001 Date of Circulation: OECD SIDS ETHYLENEDIAMINE UNEP PUBLICATIONS 3 SIDS INITIAL ASSESSMENT PROFILE CAS No. OECD SIDS ETHYLENEDIAMINE UNEP PUBLICATIONS 19 4. Hazards to the Environment 4.1 Aquatic Effects 4.1.1 Acute Toxicity The chemical was neutralized in solution prior to performing toxicity testing.


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