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Your Query "manganese" matched 175 documents out of 8787.
10 documents displayed.

0.7742 865. Mancozeb (Pesticide residues in food: 1993 evaluations Part II Toxicology)
    10-09-18, http://www.inchem.org/documents/jmpr/jmpmono/v93pr11.htm
    Summary: The NOAEL was 100 ppm, equal to 18 mg/kg bw/day for males and 22 mg/kg bw/day for females (O'Hara & DiDonato, 1985). The NOAEL was 2.3 mg/kg bw/day, equal to 2.0 mg/kg bw/day of active ingredient, based on decreased food consumption and decreased body weight in females, and decreased T4 levels in males, at 23 mg/kg bw/day (Broadmeadow, 1991a). The NOAEL was 100 ppm, equal to 13 mg/kg bw/day in males and 18 mg/kg bw/day in females, based on decreased body weight and body-weight gain and ...

0.7742 Pesticide residues in food - 2009 (JMPR Evaluations 2009 Part II Toxicological)
    07-29-11, http://www.inchem.org/documents/jmpr/jmpmono/v2009pr01.pdf
    Summary: Estimated half-lives of 51 days (fat), 50 days (skin), 19 days (liver), 28 days (kidney) and 40 days (ovaries and sciatic nerve) were derived from 14C depuration. At doses up to 1000 ppm, all female mice died by day 12, and 7 of 10 males died by day 7. At 750 ppm, fi ve females died by day 6, and at 600 ppm, two females died by day 7. There was no mortality in males in the 600 and 750 ppm dose groups. Under the study conditions utilized, the NOAEL for mice is 300 ppm, equivalent to 45 mg/kg ...

0.7742 TIN (addendum)
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v46je12.htm
    Summary: Orange juice containing 540 ppm of tin or a solution of tin citrate containing 1200 ppm of tin were administered to Wistar rats of unspecified sex. Studies of tin in food and dietary intake of tin were reviewed by Underwood (1977), Fricke et al. The mean concentrations of tin were 1.5 mg/kg in foods in lacquered cans, 88 mg/kg in food in partially lacquered cans, and 89 mg/kg in food in unlacquered cans.

0.7742 CONTAMINANTS: CADMIUM (addendum) (JECFA 52, 2004)
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v52je22.htm
    Summary: Nephrotoxicity was induced at lower concentrations of renal cadmium after parenteral exposure to cadmium-metallothionein (Sabolic et al., 2002). In all women, the rate of absorption of cadmium was significantly correlated with age, serum ferritin, serum iron, blood cadmium and urinary cadmium concentrations. In this study, urinary cadmium was considered to be a surrogate for body burden of cadmium, which reflects the overall uptake of cadmium.

0.7742 156. Bleached starches (FAO Nutrition Meetings Report Series 46a)
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v46aje25.htm
    Summary: INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY WORLD HEALTH ORGANIZATION TOXICOLOGICAL EVALUATION OF SOME FOOD COLOURS, EMULSIFIERS, STABILIZERS, ANTI-CAKING AGENTS AND CERTAIN OTHER SUBSTANCES FAO Nutrition Meetings Report Series No. 46A WHO/FOOD ADD/70.36 The content of this document is the result of the deliberations of the Joint FAO/WHO Expert Committee on Food Additives which met in Rome, 27 May - 4 June 19691 Food and Agriculture Organization of the United Nations World Health Organization ...

0.7742 472. Estragole (WHO Food Additives Series 14)
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v14je08.htm
    Summary: BIOLOGICAL DATA BIOCHEMICAL ASPECTS Metabolism Approximately 20% of a dose of estragole was excreted in the urine of outbred CD-1 mice as a conjugate of 1'-hydroxy estragole (Drinkwater et al., 1976). TOXICOLOGICAL STUDIES Special studies on pharmacological aspects Estragole caused contractions of isolated frog muscles followed by relaxation. Special studies on carcinogenicity Estragole and its 1-hydroxy metabolite caused significant increases in the incidences of hepatocellular carcinomas in...

0.7742 CADMIUM
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v46je11.htm
    Summary: Metallothionein is also induced by cadmium, and intracellular binding of cadmium to metallothionein protects against the toxicity of cadmium. The blood cadmium concentrations mainly reflected long, light exposure, as the variation in blood cadmium concentration was accounted for by urinary cadmium, serum ferritin, age and fibre intake (Berglund et al. The whole blood and erythrocyte concentrations of cadmium and urinary cadmium excretion were not affected by increased cadmium intake.

0.7742 552. Tin and stannous chloride (WHO Food Additives Series 17)
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v17je32.htm
    Summary: Three rats given fruit juice containing 540 ppm (0.054%) tin at dosages of 5.4 mg tin/rat excreted 99% of the ingested tin in their faeces but none in their urine. Twenty mice and 6 rats received 50 mg/kg bw tin citrate s.c., without tin appearing in the urine or faeces. (1971) reported no adverse effects in pigeons orally dosed with 1.5-3.0 mg tin/kg bw in fruit juice or in groups of 6 rats after single oral doses (5.4 mg tin/rat) of tin-containing fruit juices or 24-hour ad libitum ...

0.7742 899. Microcrystalline cellulose (WHO Food Additives Series 40)
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v040je03.htm
    Summary: (Avicel CL-611 or Avicel(R) Cellulose Gel is composed of 85% microcrystalline cellulose and 15% sodium carboxymethyl cellulose). Microcrystalline cellulose (Avicel) was used as a positive control in a short-term toxicity study (approximately 13 weeks) of Cellulon, a cellulose fibre. 2.2.3 Long-term toxicity/carcinogenicity studies 2.2.3.1 Rats Three groups of 50 male and 50 female rats received in their diet for 72 weeks either 30% ordinary cellulose or dry microcrystalline cellulose or ...

0.7742 833. Butylated hydroxytoluene (WHO Food Additives Series 35)
    10-09-18, http://www.inchem.org/documents/jecfa/jecmono/v35je02.htm
    Summary: Groups of male and female rats were maintained on diets containing 0 or 0.5% BHT for a period of 35 days, and then for a period on diets free of BHT. The BHT content of fat and liver of rats given diets containing 0.5 or 1% BHT for periods up to 35 and 50 days, respectively, were analyzed. Co-administration of BHA (200 mg/kg bw) with a subtoxic dose of BHT (200 mg/kg bw) enhanced the lung toxicity of BHT in male mice.


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